Aromatic heterocycles

Thiophene ring formation

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Sn2

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The unstable 1,4-dithioketone can eliminate hydrogen sulfide and form the stable aromatic heterocycle thiophene by cyclization.

T. Ozturk, E. Ertas and O. Mert, Chem. Rev., 2007, 107, 5210–5278.

 

 

 

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