Carbonyl Addition - Loss of carbonyl oxygen

Hydrazone formation

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Hydrazone Formation Mechanism

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Reaction of carbonyl with hydrazine gives a hydrazone. Hydrazine is more nucleophilic than a regular amine due to a presence of the adjacent nitrogen. Note the similary to the formation of an oxime reaction. Hydrazones generally form a mixture of geometric isomers.

 

 

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